Breast Cancer Expert Tumor Board:
Current Practice Patterns and Future Directions

This program was presented as a CME symposium.

Saturday, December 13, 2008
8:00 – 10:00 pm
Third Floor, Salon E
San Antonio Marriott Rivercenter
San Antonio, TX

Release Date: January 2009
Expiration Date: December 2009
Estimated Time to Complete Activity: 1 hour 38 minutes
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Posttest

Syllabus download (PDF)

I have read and understand the information presented on this page and agree to proceed with the educational activity.

Target Audience

This activity has been designed to meet the educational needs of academic and community medical breast oncologists as well as related healthcare professionals involved in the treatment of patients with breast cancer.

Purpose

To educate oncologists on practice pattern disparities in the treatment of metastastic breast cancer (MBC).

Program Overview

This symposium will address areas of debate in the treatment of MBC. World-renowned thought leaders will present their most intriguing cases from recent years. The intent is to highlight disparities in practice patterns relating to the treatment of MBC, particularly as they relate to drug sequencing. In addition, as new treatment choices emerge in the metastatic setting, adjuvant treatment selection becomes increasingly critical as we begin to establish a breast cancer continuum of care.

The cases will be the basis for discussion of front-line metastatic treatment sequencing/adjuvant treatment influence, metastatic disease refractory to upfront therapy, and ongoing studies/future directions. Prior to each case, audience response system surveys will be conducted to evaluate attendee practice patterns. Following each session and related panel discussions regarding treatment of the selected patients, results of the attendee practice patterns pre-case surveys will be presented to discuss academic, community, national, and international treatment disparities in breast cancer.

Learning Objectives

Upon completion of this program, participants should be better able to:

  • Review therapeutic options for MBC
  • Outline current and future therapeutic options for taxane-resistant breast cancer
  • Describe the rationale for the selection of adjuvant chemotherapy
  • Describe the effect of prior adjuvant therapy on the selection of therapy for recurrent disease
Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. PIM, IMER, and Bristol-Myers Squibb Company do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of PIM, IMER, and/or Bristol-Myers Squibb Company. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclosure of Conflicts of Interest

Postgraduate Institute for Medicine (PIM) assesses conflict of interest with its instructors, planners, managers and other individuals who are in a position to control the content of CME activities. All relevant conflicts of interest that are identified are thoroughly vetted by PIM for fair balance, scientific objectivity of studies utilized in this activity, and patient care recommendations. PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

See faculty disclosures under each Bio.

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Michael Bramwell reported no areas of conflict.

Lourdes Briz, BS, reported no areas of conflict.

Timothy J. DiChiara, PhD reported no areas of conflict.

Ninotchka Doleyres, MPH, reported no areas of conflict.

Dorothy Dulko, PhD, RN, AOCNP-C, reported no areas of conflict.

Elisheva Hertz, BSN, RN, OCN®, reported no areas of conflict.

Madelyn T. Herzfeld, BSN, RN, OCN®, reported no areas of conflict.

Davecia Ragoonath-Cameron, MS, reported no areas of conflict.

Matthew Weeks, BA, reported no areas of conflict.

Jan Hixon, MSN, RN, reported no areas of conflict.

Trace Hutchison, PharmD, reported no areas of conflict.

Linda Graham, RN, BSN, reported no areas of conflict.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

 

Jointly sponsored by:

PIM
 
Faculty
Edith A. Perez, MD (Chairperson)
Mayo Clinic
  • Bio

Dr. Perez is the director of the Breast Clinic and the Cancer Clinical Study Unit at Mayo Clinic in Jacksonville, Florida, as well as a member of the Mayo Clinic Women’s Cancer Program Steering Committee. Dr. Perez received her medical degree from the University of Puerto Rico School of Medicine in San Juan, and completed a residency in internal medicine at the Loma Linda University Medical Center in California. She has developed and is involved in a wide range of clinical trials exploring the use of new therapeutic agents for the treatment and prevention of breast cancer. She also has recently developed studies to evaluate the role of genetic markers in the development and aggressiveness of breast cancer. Dr. Perez has written more than 150 research articles in journals and books and is a frequent invited lecturer at national and international meetings each year.

Edith A. Perez, MD, reported no areas of conflict.

Clifford A. Hudis, MD
Memorial Sloan-Kettering Cancer Center
  • Bio

Dr. Hudis is chief of the breast cancer medicine service and attending physician at Memorial Sloan- Kettering Cancer Center in New York City. He also is also a professor of medicine at the Weill Medical College of Cornell University. He received his doctor of medicine from the Medical College of Pennsylvania, Philadelphia. His primary research interests include chemotherapy development, hormone therapy, novel targeted therapeutics, and supportive care. Dr. Hudis has also served on the editorial boards of several medical journals and is a member of the breast cancer committees of the Radiation Therapy Oncology Group and National Comprehensive Cancer Network.

Clifford Hudis, MD, reported a financial interest/relationship or affiliation in the form of: Consultant, Amgen, Inc., Bristol-Myers Squibb Company, Genentech BioOncology, Novartis Pharmaceuticals Corporation, Pfizer, Inc. and sanofi-aventis U.S.; Contracted Research, Kosan BioSciences.

Jose Baselga, MD
Vall d'Hebron University Hospital, Barcelona, Spain
  • Bio

Dr. Baselga is chairman of the Medical Oncology Service at the Vall d’Hebron University Hospital in Barcelona, Spain. He obtained his medical degree from the Universidad Autonoma of Barcelona and completed his fellowship in medical oncology at Memorial Sloan-Kettering Cancer Center in New York City. His research interests focus on clinical breast cancer and translational and early clinical research of growth factor receptors as well as downstream molecules as targets for breast cancer therapy. Dr. Baselga has also been involved in the clinical development of several novel agents.

Jose Baselga, MD, reported a financial interest/relationship or affiliation in the form of: Consultant, Exelixis, Inc., Novartis Pharmaceuticals Corporation, and Merck & Co., Inc.; Ownership Interest, GlaxoSmithKline plc.

 

Linda T. Vahdat, MD
Weill Medical College of Cornell University

Dr. Vahdat is associate professor of clinical medicine and director of the Breast Cancer Center at Weill Cornell Medical College in New York City. She attended medical school and completed her training in internal medicine at Mount Sinai School of Medicine in New York City. Dr. Vahdat completed a fellowship in hematology and medical oncology at Memorial Sloan-Kettering Cancer Center. She is involved in the design and conduct of phase I through III clinical trials in breast cancer and has expertise in peripheral neuropathy and the evaluation of new agents. Dr. Vahdat serves as associate editor for the American Society of Clinical Oncology Web site, People Living With Cancer (PLWC.org).

Linda T.Vahdat, MD, reported no areas of conflict.

 

Accreditation Statements

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of PIM and IMER. PIM is accredited by the ACCME to provide continuing medical education for physicians.

PIM designates this educational activity for a maximum of 1.75 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Safeguards Against Commercial Bias

IMER and PIM affirm that the content and format of its CME activities and related materials promote improvements and quality in healthcare and do not promote a specific proprietary business interest of a commercial entity. To this end, IMER and PIM employ several strategies to ensure the absence of commercial bias, including but not limited to review of all planned content for CME activities jointly-sponsored by IMER and PIM to ensure adherence to ACCME’s content validation statements and resolution of any actual or perceived conflict of interest that exist. We employ three metrics as we review your materials:

1. Fair balance

a.
Recommendations or emphasis must fairly represent and be based on a reasonable and valid interpretation of the information available on the subject matter
b.
No single product or service is overrepresented when other equal competing products or services are available for inclusion
2. Scientific objectivity of studies mentioned in the materials or used as the basis for content

3. Appropriateness of patient care recommendations made to learners

Privacy Policy

When you participate in a CME activity provided by The Postgraduate Institute of Medicine (“PIM” or “we”), we ask you for your name, degree, affiliation, street address, telephone number, fax number, and e-mail address (the “Information”). We use that Information in the following ways:

We use the Information to grade your posttest and to send you a certificate of completion of the CME activity. If we use a third-party company to grade your posttest and issue certificates of completion, we will give the Information to that company for that purpose only.

For each CME activity that you take, you must complete an evaluation questionnaire. That questionnaire asks if you are willing to participate in a follow-up survey. If you answer yes, we will use your name and contact information to send you the survey.

We may use the Information to invite you to participate in other CME activities that PIM or its affiliates may offer.

On occasion, the commercial supporter of a CME activity will ask us for a list of the people who participated in that activity, so that it may document the first level of outcomes-based evaluation in CME (ie, who attended, which medical specialties/practices were represented, how this compares to the target audience, and whether the activity needs to be repeated because significant numbers of the target audience did not attend). In that event, we will provide the supporter with your name, title, and affiliation but we will request in writing that the supporter not contact you directly for any purpose.

If our company is acquired or merged into another company, we may make the Information available to the new owner/entity to use in the ways described above, to enable it to continue our business.

Any changes to our privacy policy will be posted on our Web site.

 

Method of Participation

There are no fees for participating and receiving nursing contact hours for this activity. During the period January, 2009 through December, 2009, participants must: (1) read the learning objectives and faculty disclosures; (2) study the educational activity; (3) complete the posttest by recording the best answer to each question in the answer key on the evaluation form; (4) complete the evaluation form; and (5) mail or fax the evaluation form and posttest to IMER.

A statement of credit will be issued only upon receipt of a completed activity evaluation form and a completed posttest with a score of 70% or better. Your statement of credit will be mailed to you within 3 weeks.

Media

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